Ethics and Research with Children: A Case-Based ApproachEric Kodish M.D. Oxford University Press, 2005年3月10日 - 376 頁 In this edited volume, a diverse group of scholars present and discuss challenging cases in the field of pediatric research ethics. After years of debate and controversy, fundamental questions about the morality of pediatric research persist: Is it ever permissible to use a child as a means to an end? How much authority should parents have over decisions about research that involves young children? What should be the role of the older child in decisions about research participation? How do the dynamics of hope and desperation influence decisions about research involving dying children? Should children or their parents be paid for participation in research? What about economic incentives for doctors, researchers and the pharmaceutical industry? Most importantly, how can the twin goals of access to the benefits of clinical research and protection from research risk be reconciled? Following an introductory overview by editor Eric David Kodish, the book is divided into three sections of case studies: Research Involving Healthy Children, Research Involving At Risk Children, and Research Involving Children with Serious Illness. Each case raises compelling ethical issues, and the analysis presented in each chapter illuminate the challenges posed across a wide spectrum of both research protocols and stories of individual case-based approach, this book provides a balanced and through account of the enduring dilemmas that arise when children become research subjects. |
其他版本 - 查看全部
常見字詞
Adolescent Health adults airway hypoxia American assent assessment asthma behavior Belmont Report Bioethics blood lead concentration cancer child clinical research clinical trials conduct considered context decision developing countries direct benefit discussion disease drug effective enroll environmental ethical analysis ethical issues evaluation federal regulations fenfluramine genetic testing guidelines harm healthy children HSCT Human Subjects hypoxia individual infants informed consent innovative Institute institutional review board intervention intussusception investigators Jeremy Kennedy Krieger Institute lead abatement study minimal risk minor newborn parental permission participate in research patients payments pediatric research PEG-ADA physicians placebo placebo-controlled population pregnancy procedures prospect of direct protocol psychological questions Report require research ethics research involving children research participation research subjects response risks and benefits rotavirus vaccine scientific screening smoking social spina bifida standard surfactant Surfaxin surgical therapeutic therapy treatment type 1 diabetes utero surgery
熱門章節
第 5 頁 - The voluntary consent of the human subject is absolutely essential. This means that the person involved should have legal capacity to give consent; should be so situated as to be able to exercise free power of choice, without the intervention of any element of force, fraud, deceit, duress, over-reaching, or other ulterior form of constraint or coercion; and should have sufficient knowledge and comprehension of the elements of the subject matter...